Best DeFi-Native Crypto Cards

DeFi-native crypto cards represent the intersection of decentralised finance and everyday spending — cards built on-chain, controlled by smart contracts, and designed to let you spend directly from DeFi protocols. Sweepbase has identified 23 crypto cards that combine self-custody or hybrid custody with direct DeFi integrations, from cards that spend from Aave or Compound positions to those that let you pay with yield-bearing stablecoins. Unlike centralised exchange cards, DeFi-native cards preserve your sovereignty over assets: you hold the keys, interact with protocols, and only convert to fiat at the moment of purchase. Key differentiators include the underlying DeFi protocol, whether the card supports spending from yield-bearing positions, gas fee handling, and smart contract security audits.